Filters

IL-2R gamma Antibody, FITC Conjugated

IL-2R gamma Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, IL-2R gamma Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIL-2R gamma
SpecificityThis is a highly specific antibody against IL-2R gamma
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range135-185/369
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human IL-2R gamma
Gene ID number3561
Swiss ProtP31785
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acting through the IL2R gamma containing complexes, B cells, CD122 (IL2R beta), CD124 (IL4R alpha), CD127 (IL7R), Chemical cross linking experiments reveal that IL2R gamma is able to bind cytokines only when complexed with these other cell surface proteins, Cytokine binding to the IL2R gamma containing receptor complexes activates these tyrosine kinases, IL2, IL2 and IL15 exert their effects through cascades, IL2R gamma associates with several cytoplasmic tyrosine kinases including JAK3 (Janus Kinase 3), IL2R gamma complexed with other cell surface proteins forms receptors for the cytokines IL2, IL2R gamma forms complexes with other cell surface proteins including CD25 (IL2R alpha), IL2R gamma is also known as CD132, IL4, IL7, IL7, IL7 exerts its effects through a cascade that results in VDJ immunoglobulin gene rearrangement, IL9, In addition to interacting with other cell surface glycoproteins, JAK1, NK cells, Once activated, STAT5, Syc, The activated tyrosine kinases also phosphorylate downstream regulators including STAT3 (Signal Transducer and Activator of Transcription 3), The various cytokines that bind to IL2R gamma containing receptor complexes exert their effects through unique repertoires of cytoplasmic signaling molecules, and IL15, and IL9 exert their effects through cascades, and Lyc, and STAT6, and gamma c, and neutrophils, and others, common cytokine receptor gamma chain, creating docking sites for signaling molecules such as PI 3 kinase, macrophages, monocytes, these cytokines regulate lymphocyte development and activation, these tyrosine kinases phosphorylate their associated receptors, which activate STAT3 and STAT5, which activate the MAP kinase cascade, while IL4 activates STAT6, Interleukin 2 (IL2) receptor gamma chain (IL5212R gamma) is a cell surface glycoprotein expressed by a variety of leukocytes including T cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms CD132, CIDX, Cytokine receptor common subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, IL2RG, IMD4, Interleukin-2 receptor subunit gamma, SCIDX, SCIDX1, gammaC, P64
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIL-2R gamma Conjugated
Short name FITC Conjugated, IL-2R gamma Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, Interleukin-2R g (Antibody to)
Alternative techniqueantibodies

Similar products

Subscribe to our Newsletter