Name : IL12RB2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7317511293
| Long name | ALEXA FLUOR 488 Conjugated, IL12RB2 Polyclonal Antibody |
| Also known as | Anti-IL12RB2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IL12RB2 |
| Specificity | This is a highly specific antibody against IL12RB2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 335-385/862 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-12RB2 |
| Gene ID Number | 3595 |
| Swiss Prot | Q99665 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production, Promotes the proliferation of T-cells as well as NK cells, This subunit is the signaling component coupling to the JAK2/STAT4 pathway, Receptor for interleukin-12 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IL12RB2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | IL12RB2 |
| Short name | IL12RB2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, b 2 (Antibody to), interleukin 12 receptor |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, IL12RB2 and IDBG-638111 and ENSBTAG00000009455 and 282452, IL12RB2 and IDBG-99563 and ENSG00000081985 and 3595, Il12rb2 and IDBG-153874 and ENSMUSG00000018341 and 16162, beta 2, protein kinase binding, this GO :0004896 and cytokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0034097 and response to cytokine and biological process, this GO :0004896: cytokine receptor activity, this GO :0004896: cytokine receptor activity and also this GO :0005515: protein binding and also this GO :0019901: protein kinase binding, this GO :0005515: protein binding, this GO :0019901: protein kinase binding, interleukin 12 receptor |
| Identity | 5972 |
| Gene | IL12RB2 |
| Long gene name | interleukin 12 receptor subunit beta 2 |
| Synonyms gene name | beta 2 , interleukin 12 receptor |
| Locus | 1p31, 3 |
| Discovery year | 1997-02-10 |
| GenBank acession | U64198 |
| Entrez gene record | 3595 |
| Pubmed identfication | 9284929 8943050 |
| RefSeq identity | NM_001559 |
| Classification | Fibronectin type III domain containing Interleukin receptors |
| Havana BLAST/BLAT | OTTHUMG00000009094 |