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IL1RAP Antibody

IL1RAP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIL1RAP Primary Polyclonal Antibody
Also known asIL1RAP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIL1RAP
SpecificityThis is a highly specific antibody against IL1RAP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range300-335/570
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL1RAP/IL1R3
Gene ID number3556
Swiss ProtQ9NPH3
Tested ApplicationsWB
Recommended dilutionsWB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways, Coreceptor with IL1R1 in the IL-1 signaling system, Does not bind to interleukin-1 alone, MYD88, Recruits TOLLIP to the signaling complex, Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B, Signaling involves the recruitment of adapter molecules such as TOLLIP, The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits, binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors, Coreceptor for IL1RL2 in the IL-36 signaling system (By similarity)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C3orf13, IL-1 receptor accessory protein, IL-1R-3, IL-1R3, IL-1RAcP, IL1RAP, Interleukin-1 receptor 3, Interleukin-1 receptor accessory protein, IL1R3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIL1RAP
Short nameIL1RAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinterleukin 1 receptor accessory protein (Antibody to)
Alternative techniqueantibodies
Alternative to gene target C3orf13 and IL-1RAcP and IL1R3, Extracellular, IL1RAP and IDBG-634437 and ENSBTAG00000013205 and 539334, IL1RAP and IDBG-69682 and ENSG00000196083 and 3556, Il1rap and IDBG-150439 and ENSMUSG00000022514 and 16180, protein binding, this GO :0004871 and signal transducer activity and molecular function this GO :0004908 and interleukin-1 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0042094 and interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process, this GO :0004871: signal transducer activity, this GO :0004871: signal transducer activity and also this GO :0004908: interleukin-1 receptor activity and also this GO :0005515: protein binding, this GO :0004908: interleukin-1 receptor activity, this GO :0005515: protein binding, interleukin 1 receptor accessory protein
Identity 5995
Gene IL1RAP
Long gene name interleukin 1 receptor accessory protein
Synonyms IL-1RAcP IL1R3 C3orf13
Locus 3q28
Discovery year 1997-10-09
GenBank acession AB006537
Entrez gene record 3556
Pubmed identfication 9479509 9065432
RefSeq identity NM_001167929
Classification Immunoglobulin like domain containing Interleukin receptors TIR domain containing
Havana BLAST/BLAT OTTHUMG00000156211

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