| Long name | ALEXA FLUOR 488 Conjugated, IL2 Receptor beta (Tyr364) Antibody |
| Also known as | Anti-IL2 Receptor beta Tyr364 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IL2 Receptor beta Tyr364 |
| Specificity | This is a highly specific antibody against IL2 Receptor beta Tyr364 |
| Modification | Phosphorylation |
| Modification Site | Tyr364 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human IL2 Receptor beta around the phosphorylation site of Tyr364 |
| Gene ID Number | 3560 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | B cells, CD122 levels can be upregulated by activation stimuli such as IL2, The IL2 Receptor beta chain can combine with either the common gamma subunit (gamma c) alone or the gamma c subunit and the IL2 Receptor alpha subunit to generate intermediate or high affinity IL2 receptor complexes, This receptor chain, and macrophages, is constitutively expressed by NK cells and at lower levels by T cells, monocytes, respectively, which is also shared by the IL15 receptor, IL2 Receptor beta (CD122) is a member of the immunoglobulin superfamily that forms the high affinity IL2 receptor with CD25 and CD132 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | IL-2 TCGF |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IL2 Receptor beta (Tyr364) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene | IL2 |
| Gene target | IL2 Receptor beta (Tyr364) |
| Short name | IL2 Receptor beta (Tyr364) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, interleukin 2 Receptor b (Tyr364) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, IL-2 and lymphokine and TCGF, IL2 and IDBG-36892 and ENSG00000109471 and 3558, IL2 and IDBG-630322 and ENSBTAG00000020883 and 280822, Il2 and IDBG-140190 and ENSMUSG00000027720 and 16183, glycosphin this GO lipid binding, this GO :0001933 and negative regulation of protein phosphorylation and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002903 and negative regulation of B cell apoptotic process and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005134 and interleukin-2 receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007205 and protein kinase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0019209 and kinase activator activity and molecular function this GO :0030101 and natural killer cell activation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0030307 and positive regulation of cell growth and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031851 and kappa-type opioid receptor binding and molecular function this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0034105 and positive regulation of tissue remodeling and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043208 and glycosphin this GO lipid binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0045822 and negative regulation of heart contraction and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046013 and regulation of T cell homeostatic proliferation and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051024 and positive regulation of immunoglobulin secretion and biological process this GO :0060999 and positive regulation of dendritic spine development and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005125: cytokine activity, this GO :0005125: cytokine activity and also this GO :0005134: interleukin-2 receptor binding and also this GO :0008083: growth factor activity and also this GO :0019209: kinase activator activity and also this GO :0030246: carbohydrate binding and also this GO :0031851: kappa-type opioid receptor binding and also this GO :0043208: glycosphin this GO lipid binding, this GO :0005134: interleukin-2 receptor binding, this GO :0008083: growth factor activity, this GO :0019209: kinase activator activity, this GO :0030246: carbohydrate binding, this GO :0031851: kappa-type opioid receptor binding, this GO :0043208: glycosphin this GO lipid binding, interleukin 2 |
| Identity | 6001 |
| Long gene name | interleukin 2 |
| Synonyms name | T cell growth factor |
| Locus | 4q27 |
| Discovery year | 1986-01-01 |
| GenBank acession | U25676 |
| Entrez gene record | 3558 |
| Pubmed identfication | 3260003 |
| Classification | Interleukins |
| Havana BLAST/BLAT | OTTHUMG00000133075 |
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