| Alternative name1 | CD130, CDw130, IL-6 Receptor Subunit beta, IL-6R Subunit beta), IL-6R-beta, Interleukin-6 Signal Transducer, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha, gp130, phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta, Anti-IL6ST |
| Alternative name2 | CD130, CDw130, IL-6 Receptor Subunit beta, IL-6R Subunit beta), IL-6R-beta, Interleukin-6 Signal Transducer, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha, gp130, phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta, IL6ST |
| Alternative name3 | CD130, CDw130, IL-6 Receptor Subunit beta, IL-6R Subunit beta), IL-6R-beta, Interleukin-6 Signal Transducer, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha, gp130, phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta, IL6ST |
| Alternative name4 | IL6ST |
| Alternative name5 | CD130, CDw130, IL-6 Receptor Subunit beta, IL-6R Subunit beta), IL-6R-beta, Interleukin-6 Signal Transducer, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha, gp130, phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta, Anti -IL6ST |
| Other names | CD130 antigen, CDw130, IL-6 receptor subunit beta, IL-6R subunit beta, Interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, Oncostatin-M receptor subunit alpha, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, interleukin 6 signal transducer (gp130, interleukin receptor beta chain, interleukin-6 receptor subunit beta, membrane glycoprotein 130, membrane glycoprotein gp130, oncostatin M receptor), oncostatin-M receptor subunit alpha, interleukin-6 receptor subunit beta isoform 3 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | CD130, CDW130, GP130, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, IL-6RB, IL6ST, gp130, IL6ST |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Recognizes human IL6ST when phosphorylated at Tyr905 |
| Purification method | Affinity Purified by Protein A affinity chromatography |
| Form/Appearance | 0, 15% sodium azide, Supplied as a liquid in PBS |
| Concentration | N/A |
| Storage and shipping | Aliquot to avoid repeated freezing and thawing, Aliquots are stable for12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Gel Shift Assay (GS/EMSA), ELISA (EL/EIA) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | CD130, CDw130, IL-6 Receptor Subunit beta, IL-6R Subunit beta), IL-6R-beta, Interleukin-6 Signal Transducer, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha, gp130, phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta, IL6ST |
| Short name | CD130, CDw130, IL-6 Receptor Subunit beta, IL-6R Subunit beta) Antibody, IL-6R-beta, Interleukin-6 Signal Transducer, Membrane Glycoprotein 130, Oncostatin-M Receptor Subunit alpha, gp130, phosphorylated (Tyr905) (Interleukin-6 Receptor Subunit beta, IL6ST |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | CD130, CDw130, Interleukin-6 Receptor functionnal sequence b, Interleukin-6 Signal Transducer, Interleukin-6R functionnal sequence b) (Antibody to), Interleukin-6R-b, Membrane Glycoprotein 130, Oncostatin-M Receptor functionnal sequence a, gp130, oncostatin M receptor), phosphorylated (Tyr905) (Interleukin-6 Receptor functionnal sequence b, interleukin 6 signal transducer (gp130 |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CD130 and CDW130 and GP130 and IL-6RB, Extracellular, IL6ST and IDBG-21516 and ENSG00000134352 and 3572, Il6st and IDBG-182517 and ENSMUSG00000021756 and 16195, interleukin-27 receptor activity, oncostatin M receptor), this GO :0002675 and positive regulation of acute inflammatory response and biological process this GO :0002821 and positive regulation of adaptive immune response and biological process this GO :0004897 and ciliary neurotrophic factor receptor activity and molecular function this GO :0004915 and interleukin-6 receptor activity and molecular function this GO :0004921 and interleukin-11 receptor activity and molecular function this GO :0004923 and leukemia inhibitory factor receptor activity and molecular function this GO :0004924 and oncostatin-M receptor activity and molecular function this GO :0005127 and ciliary neurotrophic factor receptor binding and molecular function this GO :0005138 and interleukin-6 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005896 and interleukin-6 receptor complex and cellular component this GO :0005900 and oncostatin-M receptor complex and cellular component this GO :0005977 and glycogen metabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008593 and regulation of Notch signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010575 and positive regulation vascular endothelial growth factor production and biological process this GO :0010613 and positive regulation of cardiac muscle hypertrophy and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019838 and growth factor binding and molecular function this GO :0019970 and interleukin-11 binding and molecular function this GO :0019981 and interleukin-6 binding and molecular function this GO :0030425 and dendrite and cellular component this GO :0034097 and response to cytokine and biological process this GO :0038154 and interleukin-11-mediated signaling pathway and biological process this GO :0038165 and oncostatin-M-mediated signaling pathway and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042511 and positive regulation of tyrosine phosphorylation of Stat1 protein and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044297 and cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0045509 and interleukin-27 receptor activity and molecular function this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048861 and leukemia inhibitory factor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070102 and interleukin-6-mediated signaling pathway and biological process this GO :0070104 and negative regulation of interleukin-6-mediated signaling pathway and biological process this GO :0070106 and interleukin-27-mediated signaling pathway and biological process this GO :0070110 and ciliary neurotrophic factor receptor complex and cellular component this GO :0070120 and ciliary neurotrophic factor-mediated signaling pathway and biological process, this GO :0004897: ciliary neurotrophic factor receptor activity, this GO :0004897: ciliary neurotrophic factor receptor activity and also this GO :0004915: interleukin-6 receptor activity and also this GO :0004921: interleukin-11 receptor activity and also this GO :0004923: leukemia inhibitory factor receptor activity and also this GO :0004924: oncostatin-M receptor activity and also this GO :0005127: ciliary neurotrophic factor receptor binding and also this GO :0005138: interleukin-6 receptor binding and also this GO :0005515: protein binding and also this GO :0019838: growth factor binding and also this GO :0019970: interleukin-11 binding and also this GO :0019981: interleukin-6 binding and also this GO :0042803: protein homodimerization activity and also this GO :0045509: interleukin-27 receptor activity, this GO :0004915: interleukin-6 receptor activity, this GO :0004921: interleukin-11 receptor activity, this GO :0004923: leukemia inhibitory factor receptor activity, this GO :0004924: oncostatin-M receptor activity, this GO :0005127: ciliary neurotrophic factor receptor binding, this GO :0005138: interleukin-6 receptor binding, this GO :0005515: protein binding, this GO :0019838: growth factor binding, this GO :0019970: interleukin-11 binding, this GO :0019981: interleukin-6 binding, this GO :0042803: protein homodimerization activity, this GO :0045509: interleukin-27 receptor activity, 66498 and IDBG-629050 and ENSBTAG00000017745 and 522155, interleukin 6 signal transducer (gp130 |
| Identity | 6021 |
| Gene | IL6ST |
| Long gene name | interleukin 6 signal transducer |
| Synonyms gene name | interleukin 6 signal transducer (gp130, oncostatin M receptor) |
| Synonyms | GP130 CD130 |
| Synonyms name | gp130, oncostatin M receptor Interleukin-6 receptor subunit beta |
| Locus | 5q11, 2 |
| Discovery year | 1991-08-12 |
| GenBank acession | M57230 |
| Entrez gene record | 3572 |
| Pubmed identfication | 2261637 |
| RefSeq identity | NM_002184 |
| Classification | CD molecules Fibronectin type III domain containing Interleukin receptors |
| Havana BLAST/BLAT | OTTHUMG00000097043 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue