Name : INPPL1(Tyr1135) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN4085708297
| Long name | ALEXA FLUOR 488 Conjugated, INPPL1(Tyr1135) Polyclonal Antibody |
| Also known as | Anti-INPPL1 Tyr1135 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | INPPL1 Tyr1135 |
| Specificity | This is a highly specific antibody against INPPL1 Tyr1135 |
| Modification | Phosphorylation |
| Modification Site | Tyr1135 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr1135 |
| Gene ID Number | 3636 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A second and much more widely expressed PTP with SH2 domains, HCP and SHP), SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, SHPTP2 (also designated PTP1D and Syp), Several groups have independently identified a non transmembrane PTP, and cell migration, designated SHPTP1 (also known as PTP1C, has been identified, metabolic control, such as mitogenic activation, transcription regulation, which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain, The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | SHIP2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the INPPL1(Tyr1135) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | INPPL1(Tyr1135) |
| Short name | INPPL1(Tyr1135) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, inositol polyphosphate phosphatase-like 1(Tyr1135) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | INPPL1 and IDBG-63291 and ENSG00000165458 and 3636, INPPL1 and IDBG-635082 and ENSBTAG00000019167 and 783833, Inppl1 and IDBG-202184 and ENSMUSG00000032737 and 16332, OPSMD and SHIP2, Plasma membranes, SH2 domain binding, this GO :0001958 and endochondral ossification and biological process this GO :0002376 and immune system process and biological process this GO :0003779 and actin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006006 and glucose metabolic process and biological process this GO :0006644 and phospholipid metabolic process and biological process this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0006897 and endocytosis and biological process this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030175 and filopodium and cellular component this GO :0032868 and response to insulin and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0043647 and inositol phosphate metabolic process and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046856 and phosphatidylinositol dephosphorylation and biological process this GO :0097178 and ruffle assembly and biological process, this GO :0003779: actin binding, this GO :0003779: actin binding and also this GO :0005515: protein binding and also this GO :0016787: hydrolase activity and also this GO :0017124: SH3 domain binding and also this GO :0042169: SH2 domain binding, this GO :0005515: protein binding, this GO :0016787: hydrolase activity, this GO :0017124: SH3 domain binding, this GO :0042169: SH2 domain binding, inositol polyphosphate phosphatase-like 1 |
| Identity | 6080 |
| Gene | INPPL1 |
| Long gene name | inositol polyphosphate phosphatase like 1 |
| Synonyms name | 51C protein SH2 domain-containing inositol 5', -phosphatase 2 phosphatidylinositol 3, 4, 5-trisphosphate 5-phosphatase 2 |
| Locus | 11q13, 4 |
| Discovery year | 1995-05-12 |
| GenBank acession | Y14385 |
| Entrez gene record | 3636 |
| Pubmed identfication | 8530088 |
| RefSeq identity | NM_001567 |
| Classification | Phosphoinositide phosphatases Sterile alpha motif domain containing SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167879 |