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Insulin-Like Growth Factor I Receptor/Insulin Receptor, phosphorylated (Tyr1131, Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, IR) Antibody

Insulin-Like Growth Factor I Receptor/Insulin Receptor, phosphorylated (Tyr1131, Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, IR) Antibody size: 10 Blots 663

Price 663
Size 10 Blots
Alternative name1 IR), Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, phosphorylated (Tyr1131, Anti-Insulin-Like Growth Factor I Receptor/Insulin Receptor
Alternative name2 IR), Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, phosphorylated (Tyr1131, Insulin-Like Growth Factor I Receptor/Insulin Receptor
Alternative name3 IR), Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, phosphorylated (Tyr1131, Insulin-Like Growth Factor I Receptor/Insulin Receptor
Alternative name4Insulin-Like Growth Factor I Receptor/Insulin Receptor
Alternative name5 IR), Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, phosphorylated (Tyr1131, Anti -Insulin-Like Growth Factor I Receptor/Insulin Receptor
Other names 160 kDa phosphotyrosine protein, 160 kDa phosphotyrosine protein, Insulin receptor substrate 4, Phosphoprotein of 160 kDa, insulin receptor substrate 4, insulin receptor substrate 4, phosphoprotein of 160 kDa, pp160, py160, insulin receptor substrate 4
Gene nameN/A
Gene name synonimsN/A
Other gene names IRS-4, IRS-4, IRS4, PY160, pp160, py160, IRS4
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypeN/A
ClonePolyclonal antibody
Host organism Source: Human, Host: Rabbit
Species reactivityHuman
Specificity and cross-reactivity Species sequence homology: Rat (100%), Tyr1135, Tyr1136 (IGFR) or Tyr1158, Tyr1162, Tyr1163 (IR), Recognizes human and mouse IR/IGF1R when phosphorylated at Tyr1131
Purification methodAffinity Purified by immunoaffinity chromatography
Form/Appearance 0, 1mg/ml BSA (IgG, 50% glycerol, pH 7, protease free), 05% sodium azide, 3, Supplied as a liquid in PBS (without Mg2+ and Ca2+)
ConcentrationN/A
Storage and shipping Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage
Tested for:Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene target IR), Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, phosphorylated (Tyr1131, Insulin-Like Growth Factor I Receptor/Insulin Receptor
Short name IR) Antibody, Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (IGF1R, phosphorylated (Tyr1131, Insulin-Like Growth Factor I Receptor/Insulin Receptor
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name IR) (Antibody to), Tyr1135, Tyr1136/Tyr1158, Tyr1162, Tyr1163) (insulin-like growth factor 1 receptor, phosphorylated (Tyr1131, Insulin-Like Growth Factor I Receptor/Insulin Receptor
Alternative techniqueantibodies
Alternative to gene target CD221 and IGFIR and IGFR and JTK13, Cell surfaces, IGF1R and IDBG-31432 and ENSG00000140443 and 3480, IGF1R and IDBG-628659 and ENSBTAG00000021527 and 281848, Igf1r and IDBG-192339 and ENSMUSG00000005533 and 16001, this GO :0001965 and G-protein alpha-subunit binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005010 and insulin-like growth factor-activated receptor activity and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005901 and caveola and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007409 and axonogenesis and biological process this GO :0007420 and brain development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008544 and epidermis development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0010656 and negative regulation of muscle cell apoptotic process and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0001965: G-protein alpha-subunit binding, this GO :0001965: G-protein alpha-subunit binding and also this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0005010: insulin-like growth factor-activated receptor activity and also this GO :0005158: insulin receptor binding and also this GO :0005515: protein binding and also this GO :0005520: insulin-like growth factor binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0005010: insulin-like growth factor-activated receptor activity, this GO :0005158: insulin receptor binding, this GO :0005515: protein binding, this GO :0005520: insulin-like growth factor binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0031994: insulin-like growth factor I binding, this GO :0042802: identical protein binding, this GO :0043548: phosphatidylinositol 3-kinase binding, this GO :0043559: insulin binding, this GO :0043560: insulin receptor substrate binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0031994: insulin-like growth factor I binding and also this GO :0042802: identical protein binding and also this GO :0043548: phosphatidylinositol 3-kinase binding and also this GO :0043559: insulin binding and also this GO :0043560: insulin receptor substrate binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030010 and establishment of cell polarity and biological process this GO :0030238 and male sex determination and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030879 and mammary gland development and biological process this GO :0031017 and exocrine pancreas development and biological process this GO :0031175 and neuron projection development and biological process this GO :0031994 and insulin-like growth factor I binding and molecular function this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0033197 and response to vitamin E and biological process this GO :0038083 and peptidyl-tyrosine autophosphorylation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043559 and insulin binding and molecular function this GO :0043560 and insulin receptor substrate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0046328 and regulation of JNK cascade and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051054 and positive regulation of DNA metabolic process and biological process this GO :0051262 and protein tetramerization and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051389 and inactivation of MAPKK activity and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060740 and prostate gland epithelium morphogenesis and biological process this GO :0090031 and positive regulation of steroid hormone biosynthetic process and biological process, insulin-like growth factor 1 receptor
Identity 5465
Gene IGF1R
Long gene name insulin like growth factor 1 receptor
Synonyms gene name insulin-like growth factor 1 receptor
Synonyms JTK13 CD221 IGFIR MGC18216 IGFR
Locus 15q26, 3
Discovery year 1988-07-07
GenBank acession M69229
Entrez gene record 3480
Pubmed identfication 1316909
RefSeq identity NM_000875
Classification CD molecules Fibronectin type III domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000149851
Locus Specific Databases LOVD - Leiden Open Variation Database LRG_1055

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