Name : Integrin alpha 1 Antibody (ITGA1)
Supplier : NJS POLY
Price :199
SKU : GEN2819547646
| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Integrin alpha 1 (ITGA1) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the Integrin alpha 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This Integrin alpha 1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P56199 |
| Purity | Antigen affinity |
| Description | The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding, The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis, This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin, ITGA1 is the alpha 1 subunit of integrin receptors |
| Immunogen | A portion of amino acids 727-755 from the human protein was used as the immunogen for this Integrin alpha 1 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Integrin alpha 1 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Integrin alpha 1 (ITGA1) |
| Short name | Integrin alpha 1 Antibody (ITGA1) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | a 1), Integrin a 1 (Antibody to) (integrin |
| Alternative technique | antibodies |
| Alternative to gene target | BT, CD49a and VLA1, Cell surfaces, ITGA1 and IDBG-236376 and ENSG00000213949 and 3672, Itga1 and IDBG-184097 and ENSMUSG00000042284 and 109700, alpha 1, metal ion binding, this GO :0000187 and activation of MAPK activity and biological process this GO :0001669 and acrosomal vesicle and cellular component this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006936 and muscle contraction and biological process this GO :0007155 and cell adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008305 and integrin complex and cellular component this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0019903 and protein phosphatase binding and molecular function this GO :0030198 and extracellular matrix organization and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0032516 and positive regulation of phosphoprotein phosphatase activity and biological process this GO :0042059 and negative regulation of epidermal growth factor receptor signaling pathway and biological process this GO :0042311 and vasodilation and biological process this GO :0043005 and neuron projection and cellular component this GO :0043204 and perikaryon and cellular component this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0045121 and membrane raft and cellular component this GO :0045123 and cellular extravasation and biological process this GO :0045178 and basal part of cell and cellular component this GO :0046872 and metal ion binding and molecular function this GO :0048812 and neuron projection morphogenesis and biological process this GO :0060326 and cell chemotaxis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0019903: protein phosphatase binding and also this GO :0046872: metal ion binding, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0019903: protein phosphatase binding, this GO :0046872: metal ion binding, 535951, 83070 and IDBG-629417 and ENSBTAG00000016525 and 528728, integrin |
| Identity | 6134 |
| Gene | ITGA1 |
| Long gene name | integrin subunit alpha 1 |
| Synonyms gene name | alpha 1 , integrin |
| Synonyms | VLA1 CD49a |
| Locus | 5q11, 2 |
| Discovery year | 1992-02-27 |
| GenBank acession | X68742 |
| Entrez gene record | 3672 |
| Pubmed identfication | 8428973 11937138 |
| RefSeq identity | NM_181501 |
| Classification | Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000131163 |