Name : Integrin alpha 2bAntibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8076827058
| Long name | FITC Conjugated, Integrin alpha 2bPolyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Integrin alpha 2b/CD41 |
| Specificity | This is a highly specific antibody against Integrin alpha 2b/CD41 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 370-420/1033 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b |
| Gene ID number | 16399 |
| Swiss Prot | Q9QUM0 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, It recognizes the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin, Integrin alpha-IIb/beta-3 is a receptor for fibronectin |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | AI172977, CD41B, GPalpha IIb, GpIIb, Integrin alpha-IIb, Itga2b, Platelet membrane glycoprotein IIb, alphaIIb, CD41 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Gene target | Conjugated, Integrin alpha 2bAntibody |
| Short name | FITC Conjugated, Integrin alpha 2bAntibody |
| Technique | Fluorescein, antibody Conjugates, FITC |
| Label | FITC |
| Alternative name | fluorecein coupled, Integrin a 2bAntibody |
| Alternative technique | antibodies |