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Integrin alpha 2bAntibody, FITC Conjugated

Integrin alpha 2bAntibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, Integrin alpha 2bPolyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIntegrin alpha 2b/CD41
SpecificityThis is a highly specific antibody against Integrin alpha 2b/CD41
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range370-420/1033
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
Gene ID number16399
Swiss ProtQ9QUM0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, It recognizes the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin, Integrin alpha-IIb/beta-3 is a receptor for fibronectin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms AI172977, CD41B, GPalpha IIb, GpIIb, Integrin alpha-IIb, Itga2b, Platelet membrane glycoprotein IIb, alphaIIb, CD41
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS
Gene target Conjugated, Integrin alpha 2bAntibody
Short name FITC Conjugated, Integrin alpha 2bAntibody
Technique Fluorescein, antibody Conjugates, FITC
LabelFITC
Alternative name fluorecein coupled, Integrin a 2bAntibody
Alternative techniqueantibodies

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