Name : Integrin beta 1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4600167587
| Long name | ALEXA FLUOR 594 Conjugated, Integrin beta 1 Polyclonal Antibody |
| Also known as | Anti-Integrin beta 1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Integrin beta 1 |
| Specificity | This is a highly specific antibody against Integrin beta 1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 10-60/798 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin beta 1 |
| Gene ID Number | 3688 |
| Swiss Prot | P05556 |
| Tested applications | IF(ICC), IF(IHC-P) |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin, Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands, In case of HIV-1 infection, Integrin alpha-1/beta-1, Integrin alpha-3/beta-1 is a receptor for epiligrin, Integrin alpha-4/beta-1 is a receptor for VCAM1, Integrin alpha-5/beta-1 is a receptor for fibrinogen, Integrin alpha-9/beta-1 is a receptor for VCAM1, Integrin alpha-V/beta-1 is a receptor for vitronectin, Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen, Integrins alpha-2/beta-1, Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro), It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin, It recognizes the sequence Q-I-D-S in VCAM1, alpha-10/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin, alpha-2/beta-1, alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin, alpha-8/beta-1, cytotactin and osteopontin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin and CSPG4, Integrins alpha-1/beta-1 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | ITGB1L |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | Integrin beta 1 |
| Short name | Integrin beta 1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, Integrin b 1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3781 |
| Gene | ITGB1P1 |
| Long gene name | integrin subunit beta 1 pseudogene 1 |
| Synonyms gene | FNRBL |
| Synonyms gene name | beta polypeptide-like integrin beta 1 pseudogene 1 , fibronectin receptor |
| Locus | 19p13, 12 |
| Discovery year | 1989-05-19 |
| Entrez gene record | 100422691 |
| Pubmed identfication | 1979054 |
| RefSeq identity | NG_024150 |
| Havana BLAST/BLAT | OTTHUMG00000183370 |