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Integrin beta 1 Antibody, Biotin Conjugated

Integrin beta 1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Integrin beta 1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIntegrin beta 1
SpecificityThis is a highly specific antibody against Integrin beta 1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range10-60/798
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Integrin beta 1
Gene ID number3688
Swiss ProtP05556
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin, Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands, In case of HIV-1 infection, Integrin alpha-1/beta-1, Integrin alpha-3/beta-1 is a receptor for epiligrin, Integrin alpha-4/beta-1 is a receptor for VCAM1, Integrin alpha-5/beta-1 is a receptor for fibrinogen, Integrin alpha-9/beta-1 is a receptor for VCAM1, Integrin alpha-V/beta-1 is a receptor for vitronectin, Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen, Integrins alpha-2/beta-1, Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro), It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin, It recognizes the sequence Q-I-D-S in VCAM1, alpha-10/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin, alpha-2/beta-1, alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin, alpha-8/beta-1, cytotactin and osteopontin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin and CSPG4, Integrins alpha-1/beta-1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FNRB, Fibronectin receptor subunit beta, GPIIA, Glycoprotein IIa, ITGB1, Integrin beta-1, MDF2, MSK12, VLA-4 subunit beta, VLA-BETA, VLAB, CD29
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIntegrin beta 1 Conjugated
Short name Conjugated, Integrin beta 1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Integrin b 1 (Antibody to)
Alternative techniqueantibodies

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