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Integrin beta 3 Antibody

Integrin beta 3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIntegrin beta 3 Primary Polyclonal Antibody
Also known asIntegrin beta 3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIntegrin beta 3
SpecificityThis is a highly specific antibody against Integrin beta 3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range27-77/788
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin beta 3
Gene ID number3690
Swiss ProtP05106
Tested Applications ELISA, IF(ICC), IF(IHC-P), IHC-P, WB
Recommended dilutions ELISA(1:500-1000), IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Fibrinogen binding enhances SELP expression in activated platelets (By similarity), Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, In case of HIV-1 infection, Integrin alpha-IIb/beta-3 is a receptor for fibronectin, Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, plasminogen, prothrombin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin, thrombospondin and vitronectin, vitronectin and von Willebrand factor, Integrin alpha-V/beta-3 is a receptor for cytotactin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3, Integrin beta-3, Platelet membrane glycoprotein IIIa, GT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIntegrin beta 3
Short nameIntegrin beta 3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIntegrin b 3 (Antibody to)
Alternative techniqueantibodies
Identity 6157
Gene ITGB3BP
Long gene name integrin subunit beta 3 binding protein
Synonyms gene name integrin beta 3 binding protein (beta3-endonexin)
Synonyms NRIF3 HSU37139 TAP20 CENPR
Synonyms name centromere protein R beta3-endonexin
Locus 1p31, 3
Discovery year 2000-05-08
GenBank acession U37139
Entrez gene record 23421
Pubmed identfication 7593198 10490654
RefSeq identity NM_014288
Havana BLAST/BLAT OTTHUMG00000013364

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