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Integrin beta 3 Antibody, Biotin Conjugated

Integrin beta 3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Integrin beta 3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIntegrin beta 3
SpecificityThis is a highly specific antibody against Integrin beta 3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range27-77/788
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Integrin beta 3
Gene ID number3690
Swiss ProtP05106
Tested applications ELISA, IHC-P, WB
Recommended dilutions ELISA(1:500-1000), IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Fibrinogen binding enhances SELP expression in activated platelets (By similarity), Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, In case of HIV-1 infection, Integrin alpha-IIb/beta-3 is a receptor for fibronectin, Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, plasminogen, prothrombin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin, thrombospondin and vitronectin, vitronectin and von Willebrand factor, Integrin alpha-V/beta-3 is a receptor for cytotactin
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3, Integrin beta-3, Platelet membrane glycoprotein IIIa, GT
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIntegrin beta 3 Conjugated
Short name Conjugated, Integrin beta 3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Integrin b 3 (Antibody to)
Alternative techniqueantibodies

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