Name : Integrin beta 3 Antibody, Cy7 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN6276036829
| Long name | Cy7 Conjugated, Integrin beta 3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy7 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Integrin beta 3 |
| Specificity | This is a highly specific antibody against Integrin beta 3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 27-77/788 |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human Integrin beta 3 |
| Gene ID number | 3690 |
| Swiss Prot | P05106 |
| Tested applications | IF(ICC), IF(IHC-P) |
| Recommended dilutions | IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Fibrinogen binding enhances SELP expression in activated platelets (By similarity), Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen, In case of HIV-1 infection, Integrin alpha-IIb/beta-3 is a receptor for fibronectin, Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain, Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands, This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface, fibrinogen, fibronectin, laminin, matrix metalloproteinase-2, osteomodulin, osteopontin, plasminogen, prothrombin, prothrombin, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions, thrombospondin, thrombospondin and vitronectin, vitronectin and von Willebrand factor, Integrin alpha-V/beta-3 is a receptor for cytotactin |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 743nm/767nm |
| Synonyms | BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3, Integrin beta-3, Platelet membrane glycoprotein IIIa, GT |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target | Integrin beta 3 Conjugated |
| Short name | Conjugated, Integrin beta 3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy7 |
| Alternative name | cyanine 7 coupled, Integrin b 3 (Antibody to) |
| Alternative technique | antibodies |