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Integrin beta 7 Antibody (ITGB7)

Integrin beta 7 Antibody (ITGB7) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenIntegrin beta 7 (ITGB7)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Integrin beta 7 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Integrin beta 7 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P26010
PurityAntigen affinity
Description Binds to HIV-1 gp120, Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract, Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin, Interaction would involve a tripeptide L-D-I in HIV-1 gp120, Interactions involves the tripeptide L-D-T in MADCAM1, Interacts also with VCAM1 and fibronectin, It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin, an extracellular matrix component, and L-D-V in fibronectin, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease, Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT)
ImmunogenA portion of amino acids 737-765 from the human protein was used as the immunogen for this Integrin beta 7 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Integrin beta 7 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIntegrin beta 7 (ITGB7)
Short nameIntegrin beta 7 Antibody (ITGB7)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name b 7), Integrin b 7 (Antibody to) (integrin
Alternative techniqueantibodies
Alternative to gene target ITGB7 and IDBG-36071 and ENSG00000139626 and 3695, ITGB7 and IDBG-631373 and ENSBTAG00000018993 and 514031, Itgb7 and IDBG-188077 and ENSMUSG00000001281 and 16421, Plasma membranes, beta 7, metal ion binding, this GO :0001618 and virus receptor activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008305 and integrin complex and cellular component this GO :0009615 and response to virus and biological process this GO :0016020 and membrane and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0043235 and receptor complex and cellular component this GO :0046872 and metal ion binding and molecular function this GO :0050776 and regulation of immune response and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072678 and T cell migration and biological process, this GO :0001618: virus receptor activity, this GO :0001618: virus receptor activity and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0046872: metal ion binding, this GO :0004872: receptor activity, this GO :0005515: protein binding, this GO :0046872: metal ion binding, integrin
Identity 6162
Gene ITGB7
Long gene name integrin subunit beta 7
Synonyms gene name beta 7 , integrin
Locus 12q13, 13
Discovery year 1991-10-07
Entrez gene record 3695
Pubmed identfication 2040616
Classification Integrin beta subunits
Havana BLAST/BLAT OTTHUMG00000169775

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