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INTS3 Antibody, ALEXA FLUOR 488

INTS3 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, INTS3 Polyclonal Antibody
Also known asAnti-INTS3 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenINTS3
SpecificityThis is a highly specific antibody against INTS3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range960-998/1043
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human INTS3
Gene ID Number65123
Swiss ProtQ68E01
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Component of the SOSS complex, In the SOSS complex, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites, recombinational repair and maintenance of genomic stability, Component of the Integrator complex
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms FLJ21919 INT3 SOSS-A
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the INTS3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetINTS3
Short nameINTS3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, INTS3 (Antibody to)
Alternative techniqueantibodies
Identity 26153
Gene INTS3
Long gene name integrator complex subunit 3
Synonyms gene C1orf60
Synonyms gene name chromosome 1 open reading frame 60
Synonyms name sensor of single-strand DNA complex subunit A
Locus 1q21, 3
Discovery year 2005-05-13
GenBank acession BX640950
Entrez gene record 65123
Pubmed identfication 16239144
RefSeq identity NM_023015
Classification Integrator complex
Havana BLAST/BLAT OTTHUMG00000037089

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