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INTS3 Antibody, Cy5 Conjugated

INTS3 Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, INTS3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenINTS3
SpecificityThis is a highly specific antibody against INTS3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range960-998/1043
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human INTS3
Gene ID number65123
Swiss ProtQ68E01
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Component of the SOSS complex, In the SOSS complex, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites, recombinational repair and maintenance of genomic stability, Component of the Integrator complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms FLJ21919 INT3 SOSS-A
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetINTS3 Conjugated
Short name Conjugated, INTS3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, INTS3 (Antibody to)
Alternative techniqueantibodies
Identity 26153
Gene INTS3
Long gene name integrator complex subunit 3
Synonyms gene C1orf60
Synonyms gene name chromosome 1 open reading frame 60
Synonyms name sensor of single-strand DNA complex subunit A
Locus 1q21, 3
Discovery year 2005-05-13
GenBank acession BX640950
Entrez gene record 65123
Pubmed identfication 16239144
RefSeq identity NM_023015
Classification Integrator complex
Havana BLAST/BLAT OTTHUMG00000037089

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