Filters

INTS3 Antibody, FITC Conjugated

INTS3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, INTS3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenINTS3
SpecificityThis is a highly specific antibody against INTS3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range960-998/1043
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human INTS3
Gene ID number65123
Swiss ProtQ68E01
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Component of the SOSS complex, In the SOSS complex, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites, recombinational repair and maintenance of genomic stability, Component of the Integrator complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ21919 INT3 SOSS-A
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetINTS3 Conjugated
Short name FITC Conjugated, INTS3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, INTS3 (Antibody to)
Alternative techniqueantibodies
Identity 26153
Gene INTS3
Long gene name integrator complex subunit 3
Synonyms gene C1orf60
Synonyms gene name chromosome 1 open reading frame 60
Synonyms name sensor of single-strand DNA complex subunit A
Locus 1q21, 3
Discovery year 2005-05-13
GenBank acession BX640950
Entrez gene record 65123
Pubmed identfication 16239144
RefSeq identity NM_023015
Classification Integrator complex
Havana BLAST/BLAT OTTHUMG00000037089

Similar products

Subscribe to our Newsletter