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Ips-1 Antibody

Ips-1 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenIps-1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Ips-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Ips-1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q8VCF0
PurityAntigen affinity
Description Acts downstream of DDX58 and IFIH1/MDA5, IRF3 and IRF7, May activate the same pathways following detection of extracellular dsRNA by TLR3, May protect cells from apoptosis (By similarity), and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5), to coordinate pathways leading to the activation of NF-kappa-B, which detect intracellular dsRNA produced during viral replication, Required for innate immune defense against viruses
ImmunogenA portion of amino acids 1-30 from the mouse protein was used as the immunogen for this Ips-1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Ips-1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetIps-1
Short nameIps-1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIps-1 (Antibody to)
Alternative techniqueantibodies
Identity 29233
Gene MAVS
Long gene name mitochondrial antiviral signaling protein
Synonyms VISA KIAA1271 IPS-1 Cardif
Synonyms name virus-induced signaling adaptor IFN-B promoter stimulator 1 CARD adaptor inducing IFN-beta
Locus 20p13
Discovery year 2009-04-01
GenBank acession DQ174270
Entrez gene record 57506
Pubmed identfication 16125763 16153868
RefSeq identity NM_020746
Classification Caspase recruitment domain containing
Havana BLAST/BLAT OTTHUMG00000031765

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