Name : IQCG Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN2113029372
| Long name | Biotin Conjugated, IQCG Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IQCG |
| Specificity | This is a highly specific antibody against IQCG |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human IQCG |
| Gene ID number | 84223 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A modest increase in this level can result in a myriad of physiological responses, IQCG exists as two isoforms due to alternatively splicing events, IQCG forms a complex with Nup98, In acute T-lymphoid/myeloid leukemia, NUP98-IQCG complex bind co-activators and/or co-repressors, The level of intracellular calcium is tightly regulated in all eukaryotic cells, Widely distributed in nature, an O-linked glycoprotein and a component of the nuclear pore complex, most of which are mediated by calmodulin (CaM), the IQ domain forms an amphiphilic seven-turn Î, the universal calcium sensor, which suggest a role in transcriptional regulation, ±, -helix capable of binding calmodulin in a Ca2+-independent manner, IQCG is a 443 amino acid protein containing one IQ domain, Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | DKFZp434B227 DRC9 CFAP122 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | IQCG Conjugated |
| Short name | Conjugated, IQCG Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, IQCG (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25251 |
| Gene | IQCG |
| Long gene name | IQ motif containing G |
| Synonyms name | dynein regulatory complex subunit 9 |
| Locus | 3q29 |
| Discovery year | 2005-01-19 |
| GenBank acession | AL136889 |
| Entrez gene record | 84223 |
| Pubmed identfication | 11230166 23427265 24362311 |
| RefSeq identity | NM_032263 |
| Classification | Dynein regulatory complex |
| Havana BLAST/BLAT | OTTHUMG00000155408 |