Name : IQCG Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5581448191
| Long name | FITC Conjugated, IQCG Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IQCG |
| Specificity | This is a highly specific antibody against IQCG |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human IQCG |
| Gene ID number | 84223 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A modest increase in this level can result in a myriad of physiological responses, IQCG exists as two isoforms due to alternatively splicing events, IQCG forms a complex with Nup98, In acute T-lymphoid/myeloid leukemia, NUP98-IQCG complex bind co-activators and/or co-repressors, The level of intracellular calcium is tightly regulated in all eukaryotic cells, Widely distributed in nature, an O-linked glycoprotein and a component of the nuclear pore complex, most of which are mediated by calmodulin (CaM), the IQ domain forms an amphiphilic seven-turn Î, the universal calcium sensor, which suggest a role in transcriptional regulation, ±, -helix capable of binding calmodulin in a Ca2+-independent manner, IQCG is a 443 amino acid protein containing one IQ domain, Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | DKFZp434B227 DRC9 CFAP122 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | IQCG Conjugated |
| Short name | FITC Conjugated, IQCG Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, IQCG (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25251 |
| Gene | IQCG |
| Long gene name | IQ motif containing G |
| Synonyms name | dynein regulatory complex subunit 9 |
| Locus | 3q29 |
| Discovery year | 2005-01-19 |
| GenBank acession | AL136889 |
| Entrez gene record | 84223 |
| Pubmed identfication | 11230166 23427265 24362311 |
| RefSeq identity | NM_032263 |
| Classification | Dynein regulatory complex |
| Havana BLAST/BLAT | OTTHUMG00000155408 |