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IQSEC2 Antibody

IQSEC2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIQSEC2 Primary Polyclonal Antibody
Also known asIQSEC2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIQSEC2
SpecificityThis is a highly specific antibody against IQSEC2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IQSEC2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), IQSEC2 exists as three isoforms due to alternative splicing events, IQSEC2 is a component of the postsynaptic density at excitatory synapses, IQSEC2 is expressed in brain, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization, Localizing to the cytoplasm, The gene encoding IQSEC2 maps to the human X chromosome, Through the activation of ARF substrates, a condition characterized by decreased intellectual function, and interacts with ARF family members as a guanine nucleotide exchange factor, kidney and small intestine, one PH domain and a SEC7 domain, ovary, pancreas, prostate and liver, with weaker levels of expression in placenta, 478 amino acid protein that belongs to the BRAG family and contains one IQ domain, IQSEC2 is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names IQ mot and SEC7 domain-containing protein 2, IQEC2_HUMAN, Iqsec2, KIAA0522, MRX1, RP11-258C19, mKIAA0522, 1, BRAG1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIQSEC2
Short nameIQSEC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIQSEC2 (Antibody to)
Alternative techniqueantibodies
Identity 29059
Gene IQSEC2
Long gene name IQ motif and Sec7 domain 2
Synonyms gene MRX1 MRX78 MRX18
Synonyms gene name X-linked 1 (non-dysmorphic) mental retardation, X-linked 18 , X-linked 78 mental retardation, mental retardation
Synonyms KIAA0522
Locus Xp11, 22
Discovery year 2004-08-27
GenBank acession AB011094
Entrez gene record 23096
Pubmed identfication 9628581 20473311 26793055
RefSeq identity XM_291345
Classification X-linked mental retardation
Havana BLAST/BLAT OTTHUMG00000021608
Locus Specific Databases Mental Retardation database

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