Filters

IQSEC2 Antibody, Biotin Conjugated

IQSEC2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, IQSEC2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIQSEC2
SpecificityThis is a highly specific antibody against IQSEC2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human IQSEC2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), IQSEC2 exists as three isoforms due to alternative splicing events, IQSEC2 is a component of the postsynaptic density at excitatory synapses, IQSEC2 is expressed in brain, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization, Localizing to the cytoplasm, The gene encoding IQSEC2 maps to the human X chromosome, Through the activation of ARF substrates, a condition characterized by decreased intellectual function, and interacts with ARF family members as a guanine nucleotide exchange factor, kidney and small intestine, one PH domain and a SEC7 domain, ovary, pancreas, prostate and liver, with weaker levels of expression in placenta, 478 amino acid protein that belongs to the BRAG family and contains one IQ domain, IQSEC2 is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms KIAA0522
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIQSEC2 Conjugated
Short name Conjugated, IQSEC2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, IQSEC2 (Antibody to)
Alternative techniqueantibodies
Identity 29059
Gene IQSEC2
Long gene name IQ motif and Sec7 domain 2
Synonyms gene MRX1 MRX78 MRX18
Synonyms gene name X-linked 1 (non-dysmorphic) mental retardation, X-linked 18 , X-linked 78 mental retardation, mental retardation
Locus Xp11, 22
Discovery year 2004-08-27
GenBank acession AB011094
Entrez gene record 23096
Pubmed identfication 9628581 20473311 26793055
RefSeq identity XM_291345
Classification X-linked mental retardation
Havana BLAST/BLAT OTTHUMG00000021608
Locus Specific Databases Mental Retardation database

Subscribe to our Newsletter