Name : IQSEC2 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN7686444079
| Long name | Biotin Conjugated, IQSEC2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IQSEC2 |
| Specificity | This is a highly specific antibody against IQSEC2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human IQSEC2 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Defects to the IQSEC2 gene have been linked to mental retardation X-linked type 1 (MRX1), IQSEC2 exists as three isoforms due to alternative splicing events, IQSEC2 is a component of the postsynaptic density at excitatory synapses, IQSEC2 is expressed in brain, IQSEC2 may play a crucial role in cytoskeletal and synaptic organization, Localizing to the cytoplasm, The gene encoding IQSEC2 maps to the human X chromosome, Through the activation of ARF substrates, a condition characterized by decreased intellectual function, and interacts with ARF family members as a guanine nucleotide exchange factor, kidney and small intestine, one PH domain and a SEC7 domain, ovary, pancreas, prostate and liver, with weaker levels of expression in placenta, 478 amino acid protein that belongs to the BRAG family and contains one IQ domain, IQSEC2 is a 1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | KIAA0522 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | IQSEC2 Conjugated |
| Short name | Conjugated, IQSEC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, IQSEC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29059 |
| Gene | IQSEC2 |
| Long gene name | IQ motif and Sec7 domain 2 |
| Synonyms gene | MRX1 MRX78 MRX18 |
| Synonyms gene name | X-linked 1 (non-dysmorphic) mental retardation, X-linked 18 , X-linked 78 mental retardation, mental retardation |
| Locus | Xp11, 22 |
| Discovery year | 2004-08-27 |
| GenBank acession | AB011094 |
| Entrez gene record | 23096 |
| Pubmed identfication | 9628581 20473311 26793055 |
| RefSeq identity | XM_291345 |
| Classification | X-linked mental retardation |
| Havana BLAST/BLAT | OTTHUMG00000021608 |
| Locus Specific Databases | Mental Retardation database |