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IRF2 Antibody

IRF2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIRF2 Primary Polyclonal Antibody
Also known asIRF2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIRF2
SpecificityThis is a highly specific antibody against IRF2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range100-150/349
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IRF2
Gene ID number3660
Swiss ProtP14316
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also acts as an activator for several genes including H4 and IL7, Antagonizes IRF1 transcriptional activation, Constitutively binds to the ISRE promoter to activate IL7, Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth, Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names IRF2, Interferon regulatory factor 2, IRF-2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIRF2
Short nameIRF2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameinterferon regulatory factor 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007596 and blood coagulation and biological process this GO :0008283 and cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process, IRF-2, IRF2 and IDBG-46310 and ENSG00000168310 and 3660, IRF2 and IDBG-628515 and ENSBTAG00000010002 and 337916, Irf2 and IDBG-154369 and ENSMUSG00000031627 and 16363, nuclei, protein binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000975: regulatory region DNA binding, this GO :0000975: regulatory region DNA binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, interferon regulatory factor 2
Identity 6117
Gene IRF2
Long gene name interferon regulatory factor 2
Locus 4q35, 1
Discovery year 1991-05-09
Entrez gene record 3660
Pubmed identfication 2475256
Havana BLAST/BLAT OTTHUMG00000160606

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