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IRF6 Antibody, Biotin Conjugated

IRF6 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, IRF6 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIRF6
SpecificityThis is a highly specific antibody against IRF6
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human IRF6
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, IRF-1 functions as an activator of interferon transcription, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP), In addition, The two factors are structurally related, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion, particularly in their N-terminal regions, which confer DNA binding specificity, while IRF-2 binds to the same cis elements and represses IRF-1 action, Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms OFC6 VWS1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIRF6 Conjugated
Short name Conjugated, IRF6 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, interferon regulatory factor 6 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0043588 and skin development and biological process this GO :0043616 and keratinocyte proliferation and biological process this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048468 and cell development and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060337 and type I interferon signaling pathway and biological process this GO :0060644 and mammary gland epithelial cell differentiation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, IRF6 and IDBG-106452 and ENSG00000117595 and 3664, IRF6 and IDBG-638354 and ENSBTAG00000002849 and 614253, Irf6 and IDBG-209073 and ENSMUSG00000026638 and 54139, LPS and OFC6 and PIT and PPS and PPS1 and VWS and VWS1, nuclei, protein binding, this GO :0000975 and regulatory region DNA binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000975: regulatory region DNA binding, this GO :0000975: regulatory region DNA binding and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, interferon regulatory factor 6
Identity 6121
Gene IRF6
Long gene name interferon regulatory factor 6
Synonyms gene VWS LPS
Synonyms gene name Van der Woude syndrome
Locus 1q32, 2
Discovery year 1997-10-16
GenBank acession AL022398
Entrez gene record 3664
Pubmed identfication 12219090
RefSeq identity NM_006147
Havana BLAST/BLAT OTTHUMG00000036521

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