Name : IRGM Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9465364674
| Long name | Cy5, 5 Conjugated, IRGM Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IRGM |
| Specificity | This is a highly specific antibody against IRGM |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human IRGM |
| Gene ID number | 345611 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | IRGM deficient mice show defects with intracellular microbial killing, IRGM has been shown to be required for host defences against a broad range of intracellular pathogens, IRGM is primarily expressed in all cells derived from B-cell lineages, More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli, Specifically, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation, and is highly expressed in macrophages following IFN-gamma stimulation, belonging to the GTPase superfamily, phagosome maturation and autophagy, IRGM belongs to a family of interferon-gamma inducible GTPases |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | LRG47 LRG-47 IFI1 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | IRGM Conjugated |
| Short name | Conjugated, IRGM Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | M (Antibody to), cyanine 5, 5 coupled, immunity-related GTPase family |
| Alternative technique | antibodies |
| Alternative to gene target | IFI47 and IDBG-645396 and ENSBTAG00000015727 and 521987, IRGM and IDBG-306231 and ENSG00000237693 and 345611, Ifi47 and IDBG-262893 and ENSMUSG00000078920 and 15953, M, Plasma membranes, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides and molecular function this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0042995 and cell projection and cellular component this GO :0045087 and innate immune response and biological process, hydrolase activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000421 and autophagic vacuole membrane and cellular component this GO :0001891 and pha this GO cytic cup and cellular component this GO :0005525 and GTP binding and molecular function this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0016020 and membrane and cellular component this GO :0016817 and hydrolase activity, this GO :0005525: GTP binding, this GO :0005525: GTP binding and also this GO :0016817: hydrolase activity, this GO :0016817: hydrolase activity, immunity-related GTPase family |
| Identity | 29597 |
| Gene | IRGM |
| Long gene name | immunity related GTPase M |
| Synonyms gene | IRGM1 |
| Synonyms gene name | M1 , immunity-related GTPase family |
| Locus | 5q33, 1 |
| Discovery year | 2005-02-21 |
| GenBank acession | BC038539 |
| Entrez gene record | 345611 |
| Pubmed identfication | 7561525 14576437 |
| RefSeq identity | NM_001145805 |
| Havana BLAST/BLAT | OTTHUMG00000163647 |