Name : IRS-2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3871466918
| Long name | ALEXA FLUOR 488 Conjugated, IRS-2 Polyclonal Antibody |
| Also known as | Anti-IRS-2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | IRS-2 |
| Specificity | This is a highly specific antibody against IRS-2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 540-590/1338 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IRS-2 |
| Gene ID Number | 8660 |
| Swiss Prot | Q9Y4H2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Each IRS is believed to have different functions, Four members of the IRS family have been described, Summary: This gene encodes the insulin receptor substrate 2, The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, a cytoplasmic signaling molecule that mediates effects of insulin, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment, however, insulin-like growth factor 1, the distinct physiological roles of each IRS are unclear, The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | IRS2, Insulin receptor substrate 2, IRS-2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IRS-2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | IRS-2 |
| Short name | IRS-2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, IRS-2 (Antibody to) |
| Alternative technique | antibodies |