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IRS-4 Antibody, ALEXA FLUOR 594

IRS-4 Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, IRS-4 Polyclonal Antibody
Also known asAnti-IRS-4 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIRS-4
SpecificityThis is a highly specific antibody against IRS-4
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range420-470/1216
Subcellular locationCell membrane
SourceKLH conjugated synthetic peptide derived from mouse IRS-4
Gene ID Number16370
Swiss ProtQ9Z0Y7
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityMouse
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen IGF1R and FGFR1, Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity, Involved in the IGF1R mitogenic signaling pathway, May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2, May be involved in nonreceptor tyrosine kinase signaling in myoblasts, May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis, Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation, Plays a role in growth, Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis, and a complex network of intracellular signaling molecules containing SH2 domains, reproduction and glucose homeostasis, such as insulin receptor, Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms PY160 IRS-4
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetIRS-4
Short nameIRS-4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, IRS-4 (Antibody to)
Alternative techniqueantibodies
Identity 6128
Gene IRS4
Long gene name insulin receptor substrate 4
Locus Xq22, 3
Discovery year 1998-11-24
GenBank acession AF007567
Entrez gene record 8471
Pubmed identfication 9261155 9553137
RefSeq identity NM_003604
Havana BLAST/BLAT OTTHUMG00000022181
Locus Specific Databases Mental Retardation database

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