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IRS-4 Antibody, FITC Conjugated

IRS-4 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, IRS-4 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIRS-4
SpecificityThis is a highly specific antibody against IRS-4
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range420-470/1216
Subcellular locationCell membrane
SourceKLH conjugated synthetic peptide derived from mouse IRS-4
Gene ID number16370
Swiss ProtQ9Z0Y7
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityMouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background IGF1R and FGFR1, Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity, Involved in the IGF1R mitogenic signaling pathway, May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2, May be involved in nonreceptor tyrosine kinase signaling in myoblasts, May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis, Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation, Plays a role in growth, Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis, and a complex network of intracellular signaling molecules containing SH2 domains, reproduction and glucose homeostasis, such as insulin receptor, Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PY160 IRS-4
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetIRS-4 Conjugated
Short name FITC Conjugated, IRS-4 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, IRS-4 (Antibody to)
Alternative techniqueantibodies
Identity 6128
Gene IRS4
Long gene name insulin receptor substrate 4
Locus Xq22, 3
Discovery year 1998-11-24
GenBank acession AF007567
Entrez gene record 8471
Pubmed identfication 9261155 9553137
RefSeq identity NM_003604
Havana BLAST/BLAT OTTHUMG00000022181
Locus Specific Databases Mental Retardation database

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