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IRS4 Antibody

IRS4 Antibody size: 0.1ml 354

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 354
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameIRS4 Primary Polyclonal Antibody
Also known asIRS4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenIRS4
SpecificityThis is a highly specific antibody against IRS4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
SourceSynthetic peptide
Gene ID number8471
Swiss ProtO14654
Tested ApplicationsWB
Recommended dilutionsWB (1:2000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen IGF1R and FGFR1, Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity, Involved in the IGF1R mitogenic signaling pathway, May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2, May be involved in nonreceptor tyrosine kinase signaling in myoblasts, May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis, Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation, Plays a role in growth, Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis, and a complex network of intracellular signaling molecules containing SH2 domains, reproduction and glucose homeostasis, such as insulin receptor, Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 160 kDa phosphotyrosine protein, IRS4, Insulin receptor substrate 4, PY160, Phosphoprotein of 160 kDa, pp160, IRS-4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetIRS4
Short nameIRS4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameIRS4 (Antibody to)
Alternative techniqueantibodies
Identity 6128
Gene IRS4
Long gene name insulin receptor substrate 4
Synonyms PY160 IRS-4
Locus Xq22, 3
Discovery year 1998-11-24
GenBank acession AF007567
Entrez gene record 8471
Pubmed identfication 9261155 9553137
RefSeq identity NM_003604
Havana BLAST/BLAT OTTHUMG00000022181
Locus Specific Databases Mental Retardation database

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