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Islet 2 Antibody, ALEXA FLUOR 488

Islet 2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Islet 2 Polyclonal Antibody
Also known asAnti-Islet 2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenIslet 2
SpecificityThis is a highly specific antibody against Islet 2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Islet 2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character, Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates, Islet-2 is a nuclear protein that contains two N-terminal LIM domains, Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways, Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character, Somatic, but not visceral, followed by a homeodomain and a serine/ glutamine/threonine-rich C-terminus, motor neurons maintain Islet-2 expression at later embryonic stages, Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Islet 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetIslet 2
Short nameIslet 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Islet 2 (Antibody to)
Alternative techniqueantibodies
Identity 14442
Gene ICA1L
Long gene name islet cell autoantigen 1 like
Synonyms gene ALS2CR15 ALS2CR14
Synonyms gene name amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 14 islet cell autoantigen 1, candidate 15 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, 69kDa-like
Locus 2q33, 2
Discovery year 2001-01-26
GenBank acession AB053317
Entrez gene record 130026
Pubmed identfication 11586298
RefSeq identity NM_138468
Classification Classical BAR domain containing
Havana BLAST/BLAT OTTHUMG00000132856

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