Name : Islet 2 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6432345014
| Long name | ALEXA FLUOR 594 Conjugated, Islet 2 Polyclonal Antibody |
| Also known as | Anti-Islet 2 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Islet 2 |
| Specificity | This is a highly specific antibody against Islet 2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Islet 2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | An early phase of Islet-2 expression by prospective visceral motor neurons of the sympathetic preganglionic motor column is critical for the emergence of complete visceral motor neuron character, Islet-1 and Islet-2 are initially ex-pressed by all postmitotic spinal motor neurons prior to diversification of somatic and visceral neuronal fates, Islet-2 is a nuclear protein that contains two N-terminal LIM domains, Islet-2 is a transcriptional factor that defines subclasses of motor neurons that segregate into columns in the spinal cord and select distinct axon pathways, Mutations that reduce or eliminate both Islet-1 and Islet-2 activity will result in pronounced defects in visceral motor neuron generation and eroded somatic motor neuron character, Somatic, but not visceral, followed by a homeodomain and a serine/ glutamine/threonine-rich C-terminus, motor neurons maintain Islet-2 expression at later embryonic stages, Islet-2 (insulin gene enhancer protein ISL-2) is a 359 amino acid protein encoded by the human gene ISL2 |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | Islet 2 |
| Short name | Islet 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, Islet 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14442 |
| Gene | ICA1L |
| Long gene name | islet cell autoantigen 1 like |
| Synonyms gene | ALS2CR15 ALS2CR14 |
| Synonyms gene name | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 14 islet cell autoantigen 1, candidate 15 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, 69kDa-like |
| Locus | 2q33, 2 |
| Discovery year | 2001-01-26 |
| GenBank acession | AB053317 |
| Entrez gene record | 130026 |
| Pubmed identfication | 11586298 |
| RefSeq identity | NM_138468 |
| Classification | Classical BAR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000132856 |