| Long name | FITC Conjugated, ITGB3(Tyr785) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ITGB3 Tyr785 |
| Specificity | This is a highly specific antibody against ITGB3 Tyr785 |
| Modification | Phosphorylation |
| Modification site | Tyr785 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human ITGB3 around the phosphorylation site of Tyr785 |
| Gene ID number | 3690 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A given chain may combine with multiple partners resulting in different integrins, Integrin beta 3 is found along with the alpha IIb chain in platelets, Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain, Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling, The ITGB3 (Integrin beta chain beta 3) protein product is the integrin beta chain beta 3 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | CD61 GPIIIa |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ITGB3(Tyr785) Conjugated |
| Short name | FITC Conjugated, ITGB3(Tyr785) Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | antigen CD61)(Tyr785) (Antibody to), b 3 (platelet glycoprotein IIIa, fluorecein coupled, integrin |
| Alternative technique | antibodies |
| Alternative to gene target | BDPLT16 and BDPLT2 and CD61 and GP3A and GPIIIa and GT, ITGB3 and IDBG-547297 and ENSG00000259207 and 3690, antigen CD61), beta 3 (platelet glycoprotein IIIa, cell adhesion molecule binding, nuclei, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0003756 and protein disulfide isomerase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005161 and platelet-derived growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006457 and protein folding and biological process this GO :0007044 and cell-substrate junction assembly and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007411 and axon guidance and biological process this GO :0007596 and blood coagulation and biological process this GO :0008305 and integrin complex and cellular component this GO :0009986 and cell surface and cellular component this GO :0010595 and positive regulation of endothelial cell migration and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010888 and negative regulation of lipid storage and biological process this GO :0014909 and smooth muscle cell migration and biological process this GO :0016020 and membrane and cellular component this GO :0016032 and viral process and biological process this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030949 and positive regulation of vascular endothelial growth factor receptor signaling pathway and biological process this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0031258 and lamellipodium membrane and cellular component this GO :0031589 and cell-substrate adhesion and biological process this GO :0032147 and activation of protein kinase activity and biological process this GO :0032369 and negative regulation of lipid transport and biological process this GO :0035295 and tube development and biological process this GO :0042060 and wound healing and biological process this GO :0042470 and melanosome and cellular component this GO :0042802 and identical protein binding and molecular function this GO :0043184 and vascular endothelial growth factor receptor 2 binding and molecular function this GO :0043235 and receptor complex and cellular component this GO :0045087 and innate immune response and biological process this GO :0045124 and regulation of bone resorption and biological process this GO :0045715 and negative regulation of low-density lipoprotein particle receptor biosynthetic process and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050748 and negative regulation of lipoprotein metabolic process and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0050900 and leukocyte migration and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070527 and platelet aggregation and biological process this GO :0071062 and alphav-beta3 integrin-vitronectin complex and cellular component, this GO :0003756: protein disulfide isomerase activity, this GO :0003756: protein disulfide isomerase activity and also this GO :0004872: receptor activity and also this GO :0005161: platelet-derived growth factor receptor binding and also this GO :0005515: protein binding and also this GO :0042802: identical protein binding and also this GO :0043184: vascular endothelial growth factor receptor 2 binding and also this GO :0050839: cell adhesion molecule binding, this GO :0004872: receptor activity, this GO :0005161: platelet-derived growth factor receptor binding, this GO :0005515: protein binding, this GO :0042802: identical protein binding, this GO :0043184: vascular endothelial growth factor receptor 2 binding, this GO :0050839: cell adhesion molecule binding, integrin |
| Identity | 6156 |
| Gene | ITGB3 |
| Long gene name | integrin subunit beta 3 |
| Synonyms gene | GP3A |
| Synonyms gene name | antigen CD61) , beta 3 (platelet glycoprotein IIIa, integrin |
| Synonyms name | platelet glycoprotein IIIa antigen CD61 |
| Locus | 17q21, 32 |
| Discovery year | 1988-06-09 |
| Entrez gene record | 3690 |
| Pubmed identfication | 2454952 |
| RefSeq identity | NM_000212 |
| Classification | Integrin beta subunits CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000171956 |
| Locus Specific Databases | LRG_481 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue