Name : ITK Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9414382887
| Long name | ITK Primary Polyclonal Antibody |
| Also known as | ITK PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ITK |
| Specificity | This is a highly specific antibody against ITK |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ITK/PSCTK2 |
| Gene ID number | 3702 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | All members of the family contain SH3 and SH2 domains and, BPK or Emb), Bmx, Btk (previously known as Atk, ITK (also known as Emt or Tsk), ITK associates with CD28 and becomes activated subsequent to CD28 ligation, The Tec family of non receptor tyrosine kinases is composed of six proteins designated Tec, Txk (also known as Rlk) and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini, with the exception of Txk and Dsrc28C, ITK is a T cell signaling protein |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Homolog of mouse T cell itk/tsk, IL2 inducible T cell kinase, Kinase EMT, LYK, MGC126257, MGC126258, PSCTK 2, PSCTK2, T cell specic kinase, TSK, Tyrosine protein kinase, Tyrosine protein kinase ITK/TSK, Tyrosine protein kinase Lyk, EMT |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ITK |
| Short name | ITK Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | interleukin 2-inducible T-cell kinase (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, EMT and LPFS1 and LYK and PSCTK2, ITK and IDBG-55348 and ENSG00000113263 and 3702, ITK and IDBG-646384 and ENSBTAG00000000306 and 522311, Itk and IDBG-165583 and ENSMUSG00000020395 and 16428, this GO :0001816 and cytokine production and biological process this GO :0001865 and NK T cell differentiation and biological process this GO :0002250 and adaptive immune response and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006968 and cellular defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007202 and activation of phospholipase C activity and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004715: non-membrane spanning protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004715: non-membrane spanning protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0046872: metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0046872: metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0032633 and interleukin-4 production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042110 and T cell activation and biological process this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050852 and T cell receptor signaling pathway and biological process, IL2-inducible T-cell kinase |
| Identity | 6171 |
| Gene | ITK |
| Long gene name | IL2 inducible T-cell kinase |
| Synonyms gene name | IL2-inducible T-cell kinase |
| Synonyms | EMT PSCTK2 LYK |
| Locus | 5q33, 3 |
| Discovery year | 1995-12-18 |
| GenBank acession | D13720 |
| Entrez gene record | 3702 |
| Pubmed identfication | 8364206 |
| Classification | Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000130245 |
| Locus Specific Databases | LRG_189 |