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Jarid2/Jumonji Antibody, ALEXA FLUOR 594

Jarid2/Jumonji Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, Jarid2/Jumonji Polyclonal Antibody
Also known asAnti-Jarid2/Jumonji PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenJarid2/Jumonji
SpecificityThis is a highly specific antibody against Jarid2/Jumonji
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range315-365/1246
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid2/Jumonji
Gene ID Number3720
Swiss ProtQ92833
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes, Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5, Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes, In cardiac cells, In embryonic stem cells, Participates in the negative regulation of cell proliferation signaling, including heart and liver development, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases, neural tube fusion process and hematopoiesis, thereby playing a key role in differentiation of embryonic stem cells and normal development, Regulator of histone methyltransferase complexes that plays an essential role in embryonic development
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms JARID2, Jumonji/ARID domain-containing protein 2, Protein Jumonji, JMJ
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetJarid2/Jumonji
Short nameJarid2/Jumonji Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, AT rich interactive domain 2/Jumonji (Antibody to), jumonji
Alternative techniqueantibodies

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