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Jarid2/Jumonji Antibody, Cy5 Conjugated

Jarid2/Jumonji Antibody, Cy5 Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Cy5 Conjugated, Jarid2/Jumonji Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenJarid2/Jumonji
SpecificityThis is a highly specific antibody against Jarid2/Jumonji
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range315-365/1246
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human Jarid2/Jumonji
Gene ID number3720
Swiss ProtQ92833
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes, Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5, Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes, In cardiac cells, In embryonic stem cells, Participates in the negative regulation of cell proliferation signaling, including heart and liver development, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases, neural tube fusion process and hematopoiesis, thereby playing a key role in differentiation of embryonic stem cells and normal development, Regulator of histone methyltransferase complexes that plays an essential role in embryonic development
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms JARID2, Jumonji/ARID domain-containing protein 2, Protein Jumonji, JMJ
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetJarid2/Jumonji Conjugated
Short name Conjugated, Jarid2/Jumonji Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name AT rich interactive domain 2/Jumonji (Antibody to), cyanine 5 coupled, jumonji
Alternative techniqueantibodies

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