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Jarid2/Jumonji Antibody, FITC Conjugated

Jarid2/Jumonji Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, Jarid2/Jumonji Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenJarid2/Jumonji
SpecificityThis is a highly specific antibody against Jarid2/Jumonji
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range315-365/1246
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human Jarid2/Jumonji
Gene ID number3720
Swiss ProtQ92833
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes, Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5, Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes, In cardiac cells, In embryonic stem cells, Participates in the negative regulation of cell proliferation signaling, including heart and liver development, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases, neural tube fusion process and hematopoiesis, thereby playing a key role in differentiation of embryonic stem cells and normal development, Regulator of histone methyltransferase complexes that plays an essential role in embryonic development
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms JARID2, Jumonji/ARID domain-containing protein 2, Protein Jumonji, JMJ
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetJarid2/Jumonji Conjugated
Short name FITC Conjugated, Jarid2/Jumonji Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name AT rich interactive domain 2/Jumonji (Antibody to), fluorecein coupled, jumonji
Alternative techniqueantibodies

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