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JIP2 Antibody, ALEXA FLUOR 350

JIP2 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, JIP2 Polyclonal Antibody
Also known asAnti-JIP2 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenJIP2
SpecificityThis is a highly specific antibody against JIP2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JIP2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen ATF-2 and c-Jun also contain the JNK binding domain and are thought to compete with JIP-1 for JNK binding (6), Evidence suggests that JNK1 and JNK2 bind to JIP-1 with greater affinity than to ATF-2 and c-Jun, JIP-1 (for JNK interacting protein-1) has been identified as a cytoplasmic inhibitor of JNK that retains JNK in the cytoplasm, JIP-1 contains an amino terminal JNK binding domain and a carboxy terminal SH3 domain, JIP-1c (also designated islet-brain 1 or IB-1), JIP-2a, JIP-2b and JIP-3, JNK1 is activated by dual phosphorylation at a Thr-Pro-Tyr motif in response to ultraviolet (UV) light, Multiple splice variants if JIP-1, Ser-63 and Ser-73, Two additional JNK family members have been identified as JNK2 and JNK3 (3), and it functions to phosphorylate c-Jun at amino terminal serine regulatory sites, have been identified in brain (7), including JIP-1b, resulting in transcriptional activation (2-5), thereby inhibiting JNK-regulated gene expression, which are targets of the JNK signaling pathway, c-Jun NH2-terminal kinases (JNKs) are distant members of the MAP kinase family (1)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms IB2 JIP2
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetJIP2
Short nameJIP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, JIP2 (Antibody to)
Alternative techniqueantibodies
Identity 6883
Gene MAPK8IP2
Long gene name mitogen-activated protein kinase 8 interacting protein 2
Synonyms gene PRKM8IPL
Synonyms gene name PRKM8 interacting protein-like
Synonyms name islet-brain 2 JNK-interacting protein 2
Locus 22q13, 33
Discovery year 1999-10-12
GenBank acession AL021708
Entrez gene record 23542
Pubmed identfication 10490659
RefSeq identity NM_012324
Havana BLAST/BLAT OTTHUMG00000150181

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