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JMJD2B(Thr305) Antibody

JMJD2B(Thr305) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameJMJD2B(Thr305) Primary Polyclonal Antibody
Also known asJMJD2B(Thr305) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenJMJD2B Thr305
SpecificityThis is a highly specific antibody against JMJD2B Thr305
Modification(s)Phosphorylation
Modification site(s)Thr305
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human JMJD2B around the phosphorylation site of Thr305
Gene ID number23030
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen H3 Lys 27, H3 Lys 36 or H4 Lys 20, It does not demethylate Histone H3 Lys 4, JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate, JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, JMJD2B is a ubiquitously expressed nuclear protein, JMJD2C and JMJD2D, The two Tudor domains recognize and bind methylated histones and have an interdigitated structure, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, however, one JmjN domain, the unusual fold is required for its ability to bind methylated histone tails, thereby playing a role in histone code, two PHD-type zinc fingers and two Tudor domains, 064 amino acid protein encoded by the human gene JMJD2B, JMJD2B is a 1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names JHDM3B, JMJD2B, JmjC domain-containing histone demethylation protein 3A, JmjC domain-containing histone demethylation protein 3B, Jumonji domain containing protein 2B, KDM4B/JMJD2B phospho Thr305, KDM4B_HUMAN, KIAA0876, Lysine-specic demethylase 4B, p-KDM4BT305, p-KDM4BThr305, KDM4B/JMJD2B phospho T305
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetJMJD2B(Thr305)
Short nameJMJD2B(Thr305) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameJMJD2B(Thr305) (Antibody to)
Alternative techniqueantibodies
Identity 29136
Gene KDM4B
Long gene name lysine demethylase 4B
Synonyms gene JMJD2B
Synonyms gene name jumonji domain containing 2B lysine (K)-specific demethylase 4B
Synonyms KIAA0876 TDRD14B
Synonyms name tudor domain containing 14B
Locus 19p13, 3
Discovery year 2004-01-14
GenBank acession AB020683
Entrez gene record 23030
Pubmed identfication 10048485 15138608
RefSeq identity NM_015015
Classification Lysine demethylases Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000180281

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