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JMJD2D Antibody

JMJD2D Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenJMJD2D
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the JMJD2D antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis JMJD2D antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q6B0I6
PurityPurified
Description A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function, Contributions of histone demethylase activity to tumor development, Family members include JHDM1 (demethylating histone 3 at lysine 36), Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate, While most covalent histone modifications are reversible, and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9), and hormone-dependent transcriptional activation have been observed, decreases in cell proliferation, only recently has it been established that methyl groups are subject to enzymatic removal from histones, Covalent modification of histones plays critical role in regulating chromatin structure and transcription
ImmunogenA portion of amino acids 484-516 from the human protein was used as the immunogen for this JMJD2D antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the JMJD2D antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetJMJD2D
Short nameJMJD2D Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameJMJD2D (Antibody to)
Alternative techniqueantibodies
Identity 25498
Gene KDM4D
Long gene name lysine demethylase 4D
Synonyms gene JMJD2D
Synonyms gene name jumonji domain containing 2D lysine (K)-specific demethylase 4D
Synonyms FLJ10251
Locus 11q21
Discovery year 2004-01-14
GenBank acession AK001113
Entrez gene record 55693
Pubmed identfication 15138608
RefSeq identity NM_018039
Classification Lysine demethylases
Havana BLAST/BLAT OTTHUMG00000167838

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