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JMJD4 Antibody

JMJD4 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenJMJD4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the JMJD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis JMJD4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9H9V9
PurityPurified
Description A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function, Contributions of histone demethylase activity to tumor development, Family members include JHDM1 (demethylating histone 3 at lysine 36), Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate, While most covalent histone modifications are reversible, and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9), and hormone-dependent transcriptional activation have been observed, decreases in cell proliferation, only recently has it been established that methyl groups are subject to enzymatic removal from histones, Covalent modification of histones plays critical role in regulating chromatin structure and transcription
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this JMJD4 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the JMJD4 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetJMJD4
Short nameJMJD4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameJMJD4 (Antibody to)
Alternative techniqueantibodies
Identity 25724
Gene JMJD4
Long gene name jumonji domain containing 4
Synonyms FLJ12517
Synonyms name 2-oxoglutarate- and Fe(II)-dependent oxygenase C4 lysyl hydroxylase
Locus 1q42, 13
Discovery year 2005-05-18
GenBank acession AK022579
Entrez gene record 65094
Pubmed identfication 24486019
RefSeq identity NM_023007
Havana BLAST/BLAT OTTHUMG00000037698

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