Filters

JNK1+2+3 Antibody

JNK1+2+3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameJNK1+2+3 Primary Polyclonal Antibody
Also known asJNK1+2+3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenJNK1+2+3
SpecificityThis is a highly specific antibody against JNK1+2+3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range160-210/384
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from mouse JNK1/2/3
Gene ID number264192642026414
Swiss ProtQ61831
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP, Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, In this cascade, In turn, MAPK1/JNK3 phosphorylates a number of transcription factors, Participates also in neurite growth in spiral ganglion neurons, Phosphorylates the neuronal microtubule regulator STMN2, Plays regulatory roles in the signaling pathways during neuronal apoptosis, differentiation, migration and programmed cell death, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK1/JNK3, Serine/threonine-protein kinase involved in various processes such as neuronal proliferation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AI849689, AI85183, C238H4Rik, JNK, JNK1, JNK2, JNK3B1, JNK3B2, MAP kinase 1, MAP kinase p49 3F12, MAPK 1, Mapk1, Mitogen-activated protein kinase 1, Prkm1, Prkm8, Prkm9, SAPK(beta), SAPK1, Serk2, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, p493F12, p54aSAPK, p54bSAPK, JNK3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetJNK1+2+3
Short nameJNK1+2+3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameJNK1+2+3 (Antibody to)
Alternative techniqueantibodies
Identity 6881
Gene MAPK8
Long gene name mitogen-activated protein kinase 8
Synonyms gene PRKM8
Synonyms JNK JNK1 SAPK1
Synonyms name JUN N-terminal kinase
Locus 10q11, 22
Discovery year 1998-04-28
GenBank acession L26318
Entrez gene record 5599
Pubmed identfication 8137421 8654373
Classification Mitogen-activated protein kinases
Havana BLAST/BLAT OTTHUMG00000018172

Similar products

Subscribe to our Newsletter