JNK1+2+3 Antibody, Biotin Conjugated

JNK1+2+3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, JNK1+2+3 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	JNK1+2+3
Specificity	This is a highly specific antibody against JNK1+2+3
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	160-210/384
Subcellular location	Nucleus, Cytoplasm
Source	KLH conjugated synthetic peptide derived from mouse JNK1/2/3
Gene ID number	264192642026414
Swiss Prot	Q61831
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Acts in the regulation of the beta-amyloid precursor protein/APP signaling during neuronal differentiation by phosphorylating APP, Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway, In this cascade, In turn, MAPK1/JNK3 phosphorylates a number of transcription factors, Participates also in neurite growth in spiral ganglion neurons, Phosphorylates the neuronal microtubule regulator STMN2, Plays regulatory roles in the signaling pathways during neuronal apoptosis, differentiation, migration and programmed cell death, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK1/JNK3, Serine/threonine-protein kinase involved in various processes such as neuronal proliferation
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	JNK JNK1 SAPK1
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	JNK1+2+3 Conjugated
Short name	Conjugated, JNK1+2+3 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, JNK1+2+3 (Antibody to)
Alternative technique	antibodies
Identity	6881
Gene	MAPK8
Long gene name	mitogen-activated protein kinase 8
Synonyms gene	PRKM8
Synonyms name	JUN N-terminal kinase
Locus	10q11, 22
Discovery year	1998-04-28
GenBank acession	L26318
Entrez gene record	5599
Pubmed identfication	8137421 8654373
Classification	Mitogen-activated protein kinases
Havana BLAST/BLAT	OTTHUMG00000018172

JNK1+2+3 Antibody, Biotin Conjugated

JNK1+2+3 Antibody, Biotin Conjugated size: 0.1ml 333

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