JNK1 + 3 Antibody, Biotin Conjugated

JNK1 + 3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, JNK1 + 3 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	JNK1 + 3
Specificity	This is a highly specific antibody against JNK1 + 3
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	270-320/384
Subcellular location	Nucleus, Cytoplasm
Source	KLH conjugated synthetic peptide derived from human JNK1
Gene ID number	5599
Swiss Prot	P45983
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Dog, Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, MAP2K4 and MAP2K7, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrome c-mediated cell death pathway, JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, JNK1(MAPK8) is a member of the MAP kinase family
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	JNK JNK1 SAPK1
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	JNK1 + 3 Conjugated
Short name	Conjugated, JNK1 + 3 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, JNK1 and 3 (Antibody to)
Alternative technique	antibodies
Identity	6881
Gene	MAPK8
Long gene name	mitogen-activated protein kinase 8
Synonyms gene	PRKM8
Synonyms name	JUN N-terminal kinase
Locus	10q11, 22
Discovery year	1998-04-28
GenBank acession	L26318
Entrez gene record	5599
Pubmed identfication	8137421 8654373
Classification	Mitogen-activated protein kinases
Havana BLAST/BLAT	OTTHUMG00000018172

JNK1 + 3 Antibody, Biotin Conjugated

JNK1 + 3 Antibody, Biotin Conjugated size: 0.1ml 333

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