Name : JNK1 + 3 Antibody, HRP Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN3759212710
| Long name | HRP Conjugated, JNK1 + 3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | HRP Conjugated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | JNK1 + 3 |
| Specificity | This is a highly specific antibody against JNK1 + 3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 270-320/384 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human JNK1 |
| Gene ID number | 5599 |
| Swiss Prot | P45983 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Dog, Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, MAP2K4 and MAP2K7, Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity, The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis, The cell-permeable JNK inhibitory peptide may have promise as a therapeutic agent for diabetes, This kinase is activated by various cell stimuli, This kinase is also involved in UV radiation induced apoptosis, and are involved in a wide variety of cellular processes such as proliferation, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli, apoptosis and differentiation, differentiation, transcription regulation and development, which is thought to be related to cytochrome c-mediated cell death pathway, JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, JNK1(MAPK8) is a member of the MAP kinase family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | JNK JNK1 SAPK1 |
| Properties | Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase  |
| Gene target | JNK1 + 3 Conjugated |
| Short name | Conjugated, JNK1 + 3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | HRP |
| Alternative name | horseradish peroxidase coupled, JNK1 and 3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6881 |
| Gene | MAPK8 |
| Long gene name | mitogen-activated protein kinase 8 |
| Synonyms gene | PRKM8 |
| Synonyms name | JUN N-terminal kinase |
| Locus | 10q11, 22 |
| Discovery year | 1998-04-28 |
| GenBank acession | L26318 |
| Entrez gene record | 5599 |
| Pubmed identfication | 8137421 8654373 |
| Classification | Mitogen-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000018172 |