Name : JNK3 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4959473548
| Long name | Biotin Conjugated, JNK3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | JNK3 |
| Specificity | This is a highly specific antibody against JNK3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human JNK3/MAPK10 |
| Gene ID number | 5602 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Beta-arrestin 2, Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, Four alternatively spliced transcript variants encoding distinct isoforms have been reported, MAP kinases act as an integration point for multiple biochemical signals, This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs), Through its phosphorylation and nuclear localization, a receptor-regulated MAP kinase scaffold protein, and are involved in a wide variety of cellular processes such as proliferation, differentiation, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4), this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis, transcription regulation and development, which may be important in preventing neuronal apoptosis, MAPK10 (JNK3) is a member of the MAP kinase family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | JNK3 p493F12 p54bSAPK |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | JNK3 Conjugated |
| Short name | Conjugated, JNK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, JNK3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6872 |
| Gene | MAPK10 |
| Long gene name | mitogen-activated protein kinase 10 |
| Synonyms gene | PRKM10 |
| Locus | 4q21, 3 |
| Discovery year | 1998-04-28 |
| GenBank acession | U07620 |
| Entrez gene record | 5602 |
| Pubmed identfication | 8654373 12436199 |
| Classification | Mitogen-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000130604 |