Name : JNK3 Antibody (MAPK10)
Supplier : NJS POLY
Price :199
SKU : GEN7764405338
| Category | Antibody |
| Concentration | 09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form | Purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | JNK3 (MAPK10) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IHC, WB |
| Recommended dilutions | IHC (Paraffin): 1:50-1:100, Western blot: 1:1000 |
| Notes | Titration of the JNK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This JNK3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P53779 |
| Purity | Purified |
| Description | Beta-arrestin 2, Cyclin-dependent kinase 5 can phosphorylate and inhibit the activity of this kinase, MAP kinases act as an integration point for multiple biochemical signals, This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs), Through its phosphorylation and nuclear localization, a receptor-regulated MAP kinase scaffold protein, and are involved in a wide variety of cellular processes such as proliferation, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4), differentiation, is found to interact with, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis, transcription regulation and development, which may be important in preventing neuronal apoptosis, JNK3 is a member of the MAP kinase family |
| Immunogen | A portion of amino acids 1-30 from the human protein was used as the immunogen for this JNK3 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the JNK3 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | JNK3 (MAPK10) |
| Short name | JNK3 Antibody (MAPK10) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | JNK3 (Antibody to) (MAPK10) |
| Alternative technique | antibodies |
| Identity | 6872 |
| Gene | MAPK10 |
| Long gene name | mitogen-activated protein kinase 10 |
| Synonyms gene | PRKM10 |
| Synonyms | JNK3 p493F12 p54bSAPK |
| Locus | 4q21, 3 |
| Discovery year | 1998-04-28 |
| GenBank acession | U07620 |
| Entrez gene record | 5602 |
| Pubmed identfication | 8654373 12436199 |
| Classification | Mitogen-activated protein kinases |
| Havana BLAST/BLAT | OTTHUMG00000130604 |