| Long name | 117) Monoclonal Antibody, 208, JUN (1306CT545 |
| Also known as | 117) Monoclonal Antibody, 208, JUN (1306CT545 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | JUN |
| Specificity | This is a highly specific antibody against JUN |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 117, 1306CT545, 208 |
| Source | This antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from human |
| Gene ID number | 3725 |
| Swiss Prot | P05412 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:1000) |
| Cross reactivity | Mouse, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306), Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306), Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation, Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3' |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AP-1, Activator protein 1, JUN, Proto-oncogene c-Jun, Transcription factor AP-1, V-jun avian sarcoma virus 17 oncogene homolog, c-Jun, p39, AP1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 117) Monoclonal, 208, JUN (1306CT545 |
| Short name | 117) Monoclonal Antibody, 208, JUN (1306CT545 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 117) monoclonal (Antibody to), 208, jun proto-oncogene (1306CT545 |
| Alternative technique | antibodies |
| Alternative to gene target | AP-1 and AP1 and c-Jun, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007184 and SMAD protein import into nucleus and biological process this GO :0007568 and aging and biological process this GO :0007612 and learning and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009314 and response to radiation and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009987 and cellular process and biological process this GO :0010033 and response to organic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030224 and monocyte differentiation and biological process this GO :0031103 and axon regeneration and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034097 and response to cytokine and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035026 and leading edge cell differentiation and biological process this GO :0035497 and cAMP response element binding and molecular function this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042493 and response to drug and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043922 and negative regulation by host of viral transcription and biological process this GO :0043923 and positive regulation by host of viral transcription and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045657 and positive regulation of monocyte differentiation and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051365 and cellular response to potassium ion starvation and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051591 and response to cAMP and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051899 and membrane depolarization and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0070412 and R-SMAD binding and molecular function this GO :0071277 and cellular response to calcium ion and biological process this GO :0071837 and HMG box domain binding and molecular function, HMG box domain binding, JUN and IDBG-638846 and ENSBTAG00000004037 and 280831, JUN and IDBG-99221 and ENSG00000177606 and 3725, Jun and IDBG-164161 and ENSMUSG00000052684 and 16476, nuclei, this GO :0000228 and nuclear chromosome and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0001190 and RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001525 and angiogenesis and biological process this GO :0001774 and microglial cell activation and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0001889 and liver development and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005100 and Rho GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005719 and nuclear euchromatin and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001102: RNA polymerase II activating transcription factor binding and also this GO :0001190: RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005100: Rho GTPase activator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019899: enzyme binding and also this GO :0035497: cAMP response element binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0044822: poly(A) RNA binding and also this GO :0070412: R-SMAD binding and also this GO :0071837: HMG box domain binding, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001102: RNA polymerase II activating transcription factor binding, this GO :0001190: RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005100: Rho GTPase activator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0019899: enzyme binding, this GO :0035497: cAMP response element binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0044822: poly(A) RNA binding, this GO :0070412: R-SMAD binding, this GO :0071837: HMG box domain binding, jun proto-oncogene |
| Identity | 6204 |
| Gene | JUN |
| Long gene name | AP-1 transcription factor subunit , Jun proto-oncogene |
| Synonyms gene name | v-jun avian sarcoma virus 17 oncogene homolog jun oncogene |
| Synonyms | c-Jun AP-1 |
| Locus | 1p32, 1 |
| Discovery year | 1988-05-11 |
| GenBank acession | AY217548 |
| Entrez gene record | 3725 |
| Pubmed identfication | 3194415 |
| RefSeq identity | NM_002228 |
| Classification | Basic leucine zipper proteins Jun transcription factor family |
| Havana BLAST/BLAT | OTTHUMG00000008376 |
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