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Junctophilin 3 Antibody

Junctophilin 3 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long nameJunctophilin 3 Primary Polyclonal Antibody
Also known asJunctophilin 3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenJunctophilin 3
SpecificityThis is a highly specific antibody against Junctophilin 3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Junctophilin 3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen -2 and -3, Junctophilin-1 is predominantly expressed in skeletal muscle, Junctophilin-2 is expressed in heart and skeletal muscle, Junctophilin-3 is expressed in brain, Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients, The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder, The three subtypes in this family are Junctophilin-1, as well as an ER/SR membrane spanning hydrophobic C-terminal segment, but is also expressed at low levels in heart, Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names JP3, JPH3, JPH3_HUMAN, Junctophilin type 3, Junctophilin-3, Junctophilin3, TNRC22, Trinucleotide repeat-containing gene 22 protein, JP-3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetJunctophilin 3
Short nameJunctophilin 3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameJunctophilin 3 (Antibody to)
Alternative techniqueantibodies
Identity 14203
Gene JPH3
Long gene name junctophilin 3
Synonyms gene TNRC22
Synonyms gene name trinucleotide repeat containing 22
Synonyms JP-3 CAGL237 HDL2 JP3
Locus 16q24, 2
Discovery year 2000-12-08
GenBank acession AB042636
Entrez gene record 57338
Pubmed identfication 10949023 10891348
Classification Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000137656

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