Name : Junctophilin 3 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2405140627
| Long name | Junctophilin 3 Primary Polyclonal Antibody |
| Also known as | Junctophilin 3 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Junctophilin 3 |
| Specificity | This is a highly specific antibody against Junctophilin 3 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Junctophilin 3 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | -2 and -3, Junctophilin-1 is predominantly expressed in skeletal muscle, Junctophilin-2 is expressed in heart and skeletal muscle, Junctophilin-3 is expressed in brain, Junctophilins contain a cytoplasmic domain which binds to the plasma membrane, Mutant mice lacking the Jph2 gene exhibit embryonic lethality and possess cardiac myocytes that express abnormal calcium transients, The JPH3 alternatively spliced exon 2A has been suggested as a site for CTG repeat expansion leading to a Huntington disease-like autosomal dominant disorder, The three subtypes in this family are Junctophilin-1, as well as an ER/SR membrane spanning hydrophobic C-terminal segment, but is also expressed at low levels in heart, Junctophilins are components of the junctional complexes between plasma membranes and endoplasmic or sarcoplasmic reticulums present in all excitable cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | JP3, JPH3, JPH3_HUMAN, Junctophilin type 3, Junctophilin-3, Junctophilin3, TNRC22, Trinucleotide repeat-containing gene 22 protein, JP-3 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Junctophilin 3 |
| Short name | Junctophilin 3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Junctophilin 3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14203 |
| Gene | JPH3 |
| Long gene name | junctophilin 3 |
| Synonyms gene | TNRC22 |
| Synonyms gene name | trinucleotide repeat containing 22 |
| Synonyms | JP-3 CAGL237 HDL2 JP3 |
| Locus | 16q24, 2 |
| Discovery year | 2000-12-08 |
| GenBank acession | AB042636 |
| Entrez gene record | 57338 |
| Pubmed identfication | 10949023 10891348 |
| Classification | Trinucleotide repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000137656 |