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Kallikrein 6 Antibody

Kallikrein 6 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenKallikrein 6
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the Kallikrein 6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis Kallikrein 6 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q92876
PurityAntigen affinity
Description In tissue culture, Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies, Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, The KLK6 gene is mapped on 19q13, The encoded enzyme is regulated by steroid hormones, This gene is one of the fifteen subfamily members located in a cluster on chromosome 19, Upon cellular stress, and ovarian cancers, but was not detected in any metastases of these cancers, neurosin was released from mitochondria to the cytosol, prostate, suggesting a potential for involvement in Alzheimers disease, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, which resulted in the increase of degraded alpha-synuclein species, 41, Kallikrein-related peptidase 6 is a protein that in humans is encoded by the KLK6 gene
ImmunogenAn amino acid sequence from the C-terminus of human KLK6 (YTNVCRYTNWIQKTIQAK) was used as the immunogen for this Kallikrein 6 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Kallikrein 6 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetKallikrein 6
Short nameKallikrein 6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameKallikrein 6 (Antibody to)
Alternative techniqueantibodies
Identity 6367
Gene KLK6
Long gene name kallikrein related peptidase 6
Synonyms gene PRSS9 PRSS18
Synonyms gene name 18 kallikrein 6 (neurosin, protease, serine, zyme)
Synonyms Bssp Klk7 neurosin
Locus 19q13, 3
Discovery year 1997-06-09
GenBank acession U62801
Entrez gene record 5653
Pubmed identfication 9003450 16800724 16800723
RefSeq identity NM_002774
Classification Kallikreins Proteases, serine
Havana BLAST/BLAT OTTHUMG00000183098

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