Name : Kallikrein 6 Antibody
Supplier : NJS POLY
Price :389
SKU : GEN8917037606
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Kallikrein 6 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ICC, IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes | Titration of the Kallikrein 6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Kallikrein 6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | Q92876 |
| Purity | Antigen affinity |
| Description | In tissue culture, Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies, Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, The KLK6 gene is mapped on 19q13, The encoded enzyme is regulated by steroid hormones, This gene is one of the fifteen subfamily members located in a cluster on chromosome 19, Upon cellular stress, and ovarian cancers, but was not detected in any metastases of these cancers, neurosin was released from mitochondria to the cytosol, prostate, suggesting a potential for involvement in Alzheimers disease, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, which resulted in the increase of degraded alpha-synuclein species, 41, Kallikrein-related peptidase 6 is a protein that in humans is encoded by the KLK6 gene |
| Immunogen | An amino acid sequence from the C-terminus of human KLK6 (YTNVCRYTNWIQKTIQAK) was used as the immunogen for this Kallikrein 6 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Kallikrein 6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Kallikrein 6 |
| Short name | Kallikrein 6 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Kallikrein 6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6367 |
| Gene | KLK6 |
| Long gene name | kallikrein related peptidase 6 |
| Synonyms gene | PRSS9 PRSS18 |
| Synonyms gene name | 18 kallikrein 6 (neurosin, protease, serine, zyme) |
| Synonyms | Bssp Klk7 neurosin |
| Locus | 19q13, 3 |
| Discovery year | 1997-06-09 |
| GenBank acession | U62801 |
| Entrez gene record | 5653 |
| Pubmed identfication | 9003450 16800724 16800723 |
| RefSeq identity | NM_002774 |
| Classification | Kallikreins Proteases, serine |
| Havana BLAST/BLAT | OTTHUMG00000183098 |